Psychiatric Morbidity among Patients with Neoplasm
DOI:
https://doi.org/10.56056/Keywords:
Cancer, General Health questionnaire, Psychiatric comorbidityAbstract
Background and objectives: Confronting a serious illness like cancer has the ability to trigger feelings of depression, anxiety, and other mental health challenges in a considerable portion of patients. This study aims to evaluate the prevalence of psychiatric disorders in cancer patients.
Methods: The research was carried out as a cross-sectional study to assess Psychiatric morbidity at Rizgary Teaching Hospital-Oncology department and Nanakali Hospital for Hematology and Oncology, in Erbil city, Iraq. The study was initiated in April 2023 until April 2024. General health questionnaire-28 was used as a screening tool to detect psychiatric morbidity among cancer patients.
Results: The majority of the patients showed presence of psychiatric morbidity (59.6%) according to the General Health Questionnaire-28 scale. The mean General Health Questionnaire-28 score of the patients were 26.7±10, the mean score for somatic symptoms was 8.5±3.7, the mean score for anxiety and insomnia was 7.5±4.4, the mean score for social dysfunction was 7.6±1.2, and the mean score for severe depression was 3.3±3.9. Younger age is significantly associated with presence of psychiatric morbidity (46±9.52 vs. 51±6.33) (p=0.001). Gender was also significantly associated with having psychiatric morbidity, as females showed the highest prevalence (66.2%) compared to males (40%) (p<0.05). There is a statistically significant association, between type of treatment and presence of psychiatric morbidity(p=0.039).
Conclusion: The mental health issues are prevalent among individuals with cancer. Factors such as age, gender, and treatment type play a significant role in determining the likelihood of these issues occurring.
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1. Sung H, Ferlay J, Siegel RL, Laversanne M, Soerjomataram I, Jemal A, Bray F. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA Cancer J Clin. 2021 M;71(3):209-249. doi: 10.3322/caac.21660/
2. Lee BO, Choi WJ, Sung NY, Lee SK, Lee CG, Kang JI. Incidence and risk factors for psychiatric comorbidity among people newly diagnosed with cancer based on Korean national registry data. Psychooncology. 2015;24(12):1808–1814. doi: 10.1002/pon.3865/
3. Safaie N, Zeinali H, Ghahramanfard F, Mirmohammadkhani M, Moonesan M. Anxiety and depression among new cancer patients. J Family Med Prim Care. 2022 Aug;11(8):4146-4150. doi: 10.4103/jfmpc.jfmpc_1984_21/
4. Thong MSY, van Noorden CJF, Steindorf K, Arndt V. Cancer-Related Fatigue: Causes and Current Treatment Options. Curr Treat Options Oncol. 2020 Feb 5;21(2):17. doi: 10.1007/s11864-020-0707-5. Erratum in: Curr Treat Options Oncol. 2022 Mar;23(3):450-451.
5. Mehnert-Theuerkauf A, Hufeld JM, Esser P, Goerling U, Hermann M, Zimmermann T, et al. Prevalence of mental disorders, psychosocial distress, and perceived need for psychosocial support in cancer patients and their relatives stratified by biopsychosocial factors: rationale, study design, and methods of a prospective multi-center observational cohort study (LUPE study). Front Psychol. 2023 Apr 20; 14:1125545. doi: 10.3389/fpsyg.2023.1125545/
6. Nakash O, Shemesh A, Nagar M, Levav I. Cancer and common mental disorders in the community: Results of the Israel-World Mental Health Survey. Eur J Psychiat. 2012; 26:174–184.
7. Giese-Davis J, Collie K, Rancourt KM, Neri E, Kraemer HC, Spiegel D. Decrease in depression symptoms is associated with longer survival in patients with metastatic breast cancer. A secondary analysis. J Clin Oncol. 2011;29(4):413–420. doi: 10.1200/JCO.2010.28.4455/
8. Almigbal TH, Almutairi KM, Fu JB, Vinluan JM, Alhelih E, Alonazi WB, et al. Assessment of psychological distress among cancer patients undergoing radiotherapy in Saudi Arabia. Psychol Res Behav Manag. 2019 Aug 20; 12:691-700. doi: 10.2147/PRBM.S209896/
9. Roick J, Danker H, Kersting A, Dietrich A, Dietz A, Papsdorf K, et al. Predictors of psychiatric comorbidity in cancer patients at the time of their discharge from the hospital. Soc Psychiatry Psychiatr Epidemiol. 2022 Mar;57(3):553-561. doi: 10.1007/s00127-021-02138-1/
10. Riedl D, Schüßler G. Factors associated with and risk factors for depression in cancer patients - A systematic literature review. Transl Oncol. 2022 Feb; 16:101328. doi: 10.1016/j.tranon.2021.101328/
11. Hill J, Holcombe C, Clark L, Boothby MR, Hincks A, Fisher J et al. Predictors of onset of depression and anxiety in the year after diagnosis of breast cancer. Psychol Med. 2011;41(7):1429–1436. doi: 10.1017/S0033291710001868/
12. Park EM, Rosenstein DL. Depression in adolescents and young adults with cancer. Dialogues Clin Neurosci. 2015 Jun;17(2):171-80. doi: 10.31887/DCNS.2015.17.2/epark/
13. Jacobsen PB, Wagner LI. A new quality standard: The integration of psychosocial care into routine cancer care. J Clin Oncol. 2012; 30:1154–1159.
14. Carlson LE, Waller A, Mitchell AJ. Screening for distress and unmet needs in patients with cancer: Review and recommendations. J Clin Oncol. 2012; 30:1160–1177.
15. Mendoza TR, Wang XS, Cleeland CS, Morrissey M, Johnson BA, Wendt JK, et al. The rapid assessment of fatigue severity in cancer patients: use of the Brief Fatigue Inventory. Cancer. 1999 Mar 1;85(5):1186-96. doi: 10.1002/(sici)1097-0142(19990301)85:5<1186: aid-cncr24>3.0.co;2-n/
16. Sterling M. General Health Questionnaire – 28 (GHQ-28). J Physiother. 2011; 57(4): 259. https://doi.org/10.1016/S1836-9553(11)70060-1/
17. Shabu SA, Al-Tawil NG. Prevalence of childhood obesity among a sample of basic education school children in Erbil city. Middle East J Fam Med. 2010; 10 (10): 4-13.
18. Costa-Requena G, Garcia-Garijo M, Richart-Aznar P, Segura-Huerta Á. Psychiatric symptoms in a Spanish sample with hereditary cancer risk. J Community Genet. 2022 Jun;13(3):339-346. doi: 10.1007/s12687-022-00580-5/
19. Alhasnawi S, Sadik S, Rasheed M, Baban A, Al-Alak MM, Othman AY, et al. Iraq Mental Health Survey Study Group. The prevalence and correlates of DSM-IV disorders in the Iraq Mental Health Survey (IMHS). World Psychiatry. 2009;8(2):97-109.
20. Singer S, Szalai C, Briest S, Brown A, Dietz A, Einenkel J, et al. Co-morbid mental health conditions in cancer patients at working age--prevalence, risk profiles, and care uptake. Psychooncology. 2013 Oct;22(10):2291-7. doi: 10.1002/pon.3282/
21. Mehnert A, Brahler E, Faller H, Harter M, Keller M, Schulz H, et al. Four-Week Prevalence of Mental Disorders in Patients with Cancer Across Major Tumor Entities. J Clin Oncol. 2014;22(21);3540-3546.
22. Hartung TJ, Brähler E, Faller H, Härter M, Hinz A, Johansen C, et al. The risk of being depressed is significantly higher in cancer patients than in the general population: Prevalence and severity of depressive symptoms across major cancer types. Eur J Cancer. 2017 Feb; 72:46-53. doi: 10.1016/j.ejca.2016.11.017/
23. Bergerot CD, Mitchell HR, Ashing KT, Kim Y. A prospective study of changes in anxiety, depression, and problems in living during chemotherapy treatments: effects of age and gender. Support Care Cancer. 2017 Jun;25(6):1897-1904. doi: 10.1007/s00520-017-3596-9. Epub 2017 Feb 2.
24. Niedzwiedz CL, Knifton L, Robb KA, Katikireddi SV, Smith DJ. Depression and anxiety among people living with and beyond cancer: a growing clinical and research priority. BMC Cancer. 2019 Oct 11;19(1):943. doi: 10.1186/s12885-019-6181-4/
25. Smith HR. Depression in cancer patients: pathogenesis, implications and treatment (review) Oncol Lett. 2015;9(4):1509–1514. doi: 10.3892/ol.2015.2944/
26. Ismail MF, Lavelle C, Cassidy EM. Steroid-induced mental disorders in cancer patients: a systematic review. Future Oncol. 2017;13(29):2719–2731. doi: 10.2217/fon-2017-0306/
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