Dorzolamide Hydrochloride %2 and Timolol Maleate %0.5 Fixed Combination in Lowering Intraocular Pressure after Phacoemulsification cataract Surgery

Abdulrahman Alaa  Makki; Ahmed Kareem  Joma; Ahmed Ismaeel  Alnuaimy; Eman Hussein  Alwan

doi:10.56056/amj.2017.16

Authors

Abdulrahman Alaa Makki MBChB, Higher Diploma candidate
Ahmed Kareem Joma Head of Ophthalmology Department, MBChB, PhD, (Ophth)
Ahmed Ismaeel Alnuaimy Hawler medical university, College of Medicine, Department of Surgery
Eman Hussein Alwan Hawler medical university, College of Medicine, Department of Surgery

DOI:

https://doi.org/10.56056/amj.2017.16

Keywords:

Dorzolamide, Timolol, Cataract surgery

Abstract

Background and objectives: To evaluate the role of dorzolamide –timolol fixed combination in lowering intraocular pressure (IOP) after cataract surgery.

Methods: The study included 94 eyes of 89 patients who underwent cataract surgery and intraocular lens implantation. Patients planed for phacoemulsification were assigned to 1 of 2 groups. The treatment group received 1 drop of dorzolamide-timolol fixed combination immediately after surgery, and the control group received no treatment. The IOP was measured preoperatively and at 6 hours and 24 hours post- operatively.

Results: The mean IOP change was lower in the treatment group than in the control group at 6 hours postoperatively. The difference between the mean IOP a value of the two groups at 6 hours postoperatively was found to be statistically significant. Twenty-four hours after the surgery, the mean IOP change was still higher in the control group when compared to the treatment group.

Conclusions: The fixed combination dorzolamide-timolol can effectively lower IOP after phacoemulsification cataract surgery.

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