Thyroid dysfunction and autoantibodies among patients infected with Covid 19 in Erbil city /IRAQ

Authors

  • Halgurd Fathulla Ahmed M.B.Ch.B., F.I.B.M.S; Assistant Professor in Internal Medicine-Director of training Kurdistan higher council of medical specialties, Consultant physician; Rizgary Teaching Hospital, Erbil-Kurdistan region/Iraq
  • Esra Omar Hameed M.B.Ch.B., FKBMS; Lecturer Department of Medicine College of Medicine, Hawler Medical University, Erbil Teaching Hospital, Erbil-Kurdistan region/Iraq
  • Yahya Kamal Mohammed Ali M.B.Ch.B., FKBMS; Lecturer, Department of Medicine College of Medicine, Hawler Medical University, Erbil Teaching Hospital, Erbil-Kurdistan region/Iraq

DOI:

https://doi.org/10.56056/amj.2023.230

Keywords:

Corona virus, Thyroid autoantibodies, Thyroid peroxidase

Abstract

Background and objectives:  Autoimmune thyroid diseases or specifically Anti-thyroid peroxidase antibodies increasing after corona virus infection pandemic. This study investigating Anti-thyroperoxidase, anti-thyroid stimulating receptor antibodies in conjunction with traditional thyroid markers after corona virus infection hoping that this would aid in reduction of enduring morbidity and associated health concerns.

Methods: This cross-sectional study was conducted in Rizgary Teaching Hospital and Erbil Teaching Hospital in Erbil, Iraq, within the period of February to September 2022. The study comprised hundred patients; 80 females and 20 males, these patients had clinical symptoms suspecting thyroid abnormalities and were suspected for having a sort of thyroid disease. They had abnormal thyroid function tests, with investigating thyroid autoantibodies and corona virus infection. Investigations include thyroid function test and antithyroid antibodies.

Results: The level of Anti-thyroid peroxidase antibodies was positive among 75 hypothyroidism patients than among hyperthyroidism cases 2, p-value 0.012. Positive Anti-thyroperoxidase antibodies and hypothyroidism were significantly more common among corona virus infected cases, p-value 0.012 and 0.0109 respectively.  However; anti-thyroid stimulating hormone receptor antibody was positive only among hyperthyroidism group (18%); p-value was significant 0.019.

Conclusions: This study confirmed the correlation between thyroid function test, Anti-thyroperoxidase antibodies values and corona virus infection. Autoimmune thyroid diseases are more common among female cases, in addition; antithyroid antibodies especially Anti-thyroperoxidase antibodies were more common among female patients. There was high prevalence of both hypothyroidism and positive anti-TPO Ab in COVID-19 cases.

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Published

2023-12-05

How to Cite

Ahmed, H. F. ., Hameed, E. O. ., & Ali, Y. K. M. . (2023). Thyroid dysfunction and autoantibodies among patients infected with Covid 19 in Erbil city /IRAQ . AMJ (Advanced Medical Journal) , 8(2), 164-170. https://doi.org/10.56056/amj.2023.230

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