Assessment of cardiac troponins status in patients on regular hemodialysis

Raman Ameer  Muhammed; Hussein Yousif  Sinjari

doi:10.56056/amj.2025.316

Authors

Raman Ameer Muhammed M.B.Ch.B, Internal medicine candidate at KHCMS
Hussein Yousif Sinjari M.B.Ch.B, DM, CABM, Internal medicine specialist

DOI:

https://doi.org/10.56056/amj.2025.316

Keywords:

Cardiac troponin I, Cardiac troponin T, Hemodialysis, High-sensitive cardiac troponin

Abstract

Background and objectives: heart disease is a significant contributor to both fatalities and health issues among patients undergoing regular hemodialysis. Cardiac Troponins serve as sensitive indicators of heart muscle injury, playing a vital role in diagnosing acute coronary syndrome. The aim of this study is to assess cardiac troponins status in an Iraqi cohort of asymptomatic Hemodialysis patients.

Methods: One-hundred-thirty-six asymptomatic hemodialysis patients who visited the hemodialysis center at the Hawler Teaching Hospital in Erbil, Iraq, between August 2022 and May 2023 participated in this cohort. Recorded were demographic and baseline characteristics. A battery of laboratory tests was conducted, including high sensitivity cardiac troponin T, cardiac troponin T, and I. Correlations were made between different variables

Result: The occurrence rates of increased cardiac troponin T, and I, and high sensitivity cardiac troponin T among asymptomatic hemodialysis patients were 25%, 7.4%, and 76.5%, respectively. Cardiac troponin T alone showed a significant positive correlation with the duration of dialysis treatment (p<0.05), while cardiac troponin I was significantly associated with dyslipidemia (P<0.05).

Conclusion: The majority of asymptomatic hemodialysis patients have elevated cardiac troponin levels, particularly high sensitivity cardiac troponin T. Both cardiac troponins were positively associated with prior history of coronary artery disease, and low serum albumin. Cardiac troponin T was positively correlated with dialysis vintage.

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