Oligohydramnios in Third Trimester and Perinatal Outcomes

Authors

  • Dlsoz Emad Mohammed MBChB, Gynecology and Obstetrics trainee, Kurdistan Region, Iraq.
  • Rozhan Yaseen Khalil MBChB, FICS, HDOG, FICOG, GABOG, Assistant Professor Obstetrics and Gynecology Kurdistan Board of Medical Specialties (KBMS), Sulaimani Maternity Teaching Hospital

DOI:

https://doi.org/10.56056/amj.2025.373

Keywords:

Amniotic fluid, Apgar score, Oligohydramnios, Third trimester

Abstract

Background and objective: Oligohydramnios has been reported to be correlated with unfavorable outcomes in pregnancy, including fetal distress and stillbirth. So, this study aimed to examine the association between oligohydramnios diagnosed during the third trimester of pregnancy and perinatal outcomes.

Methods: A prospective observational study was conducted on 55 pregnant women diagnosed with oligohydramnios in Sulaimani Maternity Teaching Hospital, Sulaimaniyah, Iraq, from 15 May 2022 to 30 May 2023. A convenient sampling method was used to collect data from pregnant women with gestational ages of 28 to 41 weeks. Using ultrasound, the amniotic fluid index was measured to analyze the perinatal outcomes, and then correlations between different variables were determined.

Results: Highly significant correlations were found between mean women’s age, gestational age, gravida, para, Apgar score 5 minutes after delivery, newborn weight and mean amniotic fluid index levels (p<0.001). Most women (50.9%) received antenatal care >4 times, had <2 years’ pregnancy interval (96.4%), had emergency cesarean section (67.3%), and without induction of labor (94.5%). Most patients did not have any medical disorders (94.5%) or obstetrical disorders (65.5%); however, pregnancy-induced hypertension was the most common disorder (21.8%), followed by gestational diabetes mellitus (7.3%). Additionally, most infants were born alive with average Apgar scores (78.18%), whereas ten infants had low Apgar scores and were admitted to the neonatal intensive care unit.

Conclusion: Women affected with oligohydramnios were likely to experience unfavorable perinatal outcomes, including admission to the neonatal intensive care unit and stillbirth.

Downloads

Download data is not yet available.

References

1.Rabie N, Magann E, Steelman S, Ounpraseuth S. Oligohydramnios in complicated and uncomplicated pregnancy: a systematic review and meta?analysis. Ultrasound Obstet Gynecol. 2017;49(4):442-449.

2.Hughes DS, Magann EF, Whittington JR, Wendel MP, Sandlin AT, Ounpraseuth ST. Accuracy of the ultrasound estimate of the amniotic fluid volume (amniotic fluid index and single deepest pocket) to identify actual low, normal, and high amniotic fluid volumes as determined by quantile regression. J Ultrasound Med. 2020, 39(2):373-378.

3.Huri M, Di Tommaso M, Seravalli V. Amniotic fluid disorders: from prenatal management to neonatal outcomes. Children 2023;10(3):561.

4.Figueroa L, McClure EM, Swanson J, Nathan R, Garces AL, Moore JL, et al. Oligohydramnios: a prospective study of fetal, neonatal and maternal outcomes in low-middle income countries. Reprod Health 2020; 17:1-7.

5.Bumrah S, Grover S, Kaur K, Rajora P, Tapasvi I. Clinico-epidemiologic profile and perinatal outcome of patients with oligohydramnios in third trimester in a tertiary care hospital. Int J Reprod Contracept Obstet Gynecol. 2023;12(5):1222-1227.

6.Addisu D, Asres A, Gedefaw G, Asmer S. Prevalence of meconium-stained amniotic fluid and its associated factors among women who gave birth at term in Felege Hiwot comprehensive specialized referral hospital, North West Ethiopia: a facility based cross-sectional study. BMC Pregnancy Childb. 2018; 18:1-7.

7.Panda S, Jayalakshmi M, Kumari SG, Mahalakshmi G, Srujan Y, Anusha V. Oligoamnios and perinatal outcome. J Obstet Gynecol India 2017; 67:104-108.

8.Mihretie GN, Habitamu A. Pregnancy outcomes among women who gave birth at health institutions: A cross?sectional study. Health Sci Rep. 2022;5(5): e843.

9.Li PC, Tsui WL, Ding DC. The Association between Cervical Length and Successful Labor Induction: A Retrospective Cohort Study. Int J Environ Res Public Health 2023;20(2):1138.

10.Twesigomwe G, Migisha R, Agaba DC, Owaraganise A, Aheisibwe H, Tibaijuka L, et al. Prevalence and associated factors of oligohydramnios in pregnancies beyond 36 weeks of gestation at a tertiary hospital in southwestern Uganda. BMC Pregnancy Childb. 2022;22(1):610.

11.Capone V, Persico N, Berrettini A, Decramer S, De Marco EA, De Palma D, et al. Definition, diagnosis and management of fetal lower urinary tract obstruction: consensus of the ERKNet CAKUT-Obstructive Uropathy Work Group. Nat Rev Urol. 2022;19(5):295-303.

12.Molla M, Mengistu Z, Tsehaye W, Sisay G. Magnitude and associated factors of adverse perinatal outcomes among women with oligohydramnios at 3rd trimester at University of Gondar comprehensive specialized hospital, North West Ethiopia. Front Glob Women's Health 2023; 3:958617.

13.Shinde A, Chaudhari K, Dewani D, Shrivastava D. Effect of amino acid infusion on amniotic fluid index in pregnancies associated with oligohydramnios and fetal growth restriction. Cureus 2023;15(5).

14.Kalambe M, Ambad R, Jungari M, Shrivastava D, Kalambe A. A Clinical Study of Perinatal Outcome and its Relation to Oligohydramnios in Pregnant Women at Term. Indian J Forensic Med Toxicol. 2020;14(4):6541-6545.

15.Sharma A, Dashora S, Sharma R, Chandra K, Gunawat MS. To study the effect of L-arginine in oligohydramnios to improve perinatal outcome. IOSR J Dent Med Sci. 2017;16(4):16-19.

16.Soni A, Garg S, Patel K, Patel Z. Role of l-Arginine in Oligohydramnios. J Obstet Gynecol India 2016; 66:279-283.

17.Y?ld?r?m SB, Y?lmaz K?A, Gulerman C. The effect of active and passive maternal smoking during pregnancy on the uterine artery blood flow and obstetric outcomes: a prospective study. Cureus 2023;15(2).

18.Hou L, Wang X, Hellerstein S, Zou L, Ruan Y, Zhang W. Delivery mode and perinatal outcomes after diagnosis of oligohydramnios at term in China. J Matern Fetal Neonatal Med. 2020;33(14):2408-2414.

19.Haruyama R, Gilmour S, Ota E, Abe SK, Rahman MM, Nomura S, et al. Causes and risk factors for singleton stillbirth in Japan: Analysis of a nationwide perinatal database, 2013–2014. Sci Rep. 2018;8(1):4117.

20.Nisa SU, Shaikh AA, Kumar R. Maternal and fetal outcomes of pregnancy-related hypertensive disorders in a tertiary care hospital in Sukkur, Pakistan. Cureus 2019; 11(8).

21.Long SY, Yang Q, Chi R, Luo L, Xiong X, Chen ZQ. Maternal and neonatal outcomes resulting from antepartum hemorrhage in women with placenta previa and its associated risk factors: A single-center retrospective study. Ther Clin Risk Manag. 2021:31-38.

22.Huang S, Yitayew M, Rozycki HJ. The contribution of low Apgar scores in identifying neonates with short-term morbidities in a large single center cohort. J Perinatol 2024;44(6):865-872.

23.Mathuriya G, Verma M, Rajpoot S. Comparative study of maternal and fetal outcome between low and normal amniotic fluid index at term. Int J Reprod Contracept Obstet Gynecol. 2017;6(2):640-645.

24.Janas P, Rado-Pokracka M, Nowak M, Staro A, Wilczy?ska G, Brzozowska M, et al. Effect of oligohydramnios on the accuracy of sonographic foetal weight estimation in at term pregnancies. Taiwan J Obstet Gynecol. 2019;58(2):278-281.

Downloads

Published

2025-09-09

Issue

Section

Articles

How to Cite

Oligohydramnios in Third Trimester and Perinatal Outcomes. (2025). AMJ (Advanced Medical Journal) , 10(3), 95-102. https://doi.org/10.56056/amj.2025.373