A Possible Role for Structured Water Utilizing Nanotechnology in Preventing Recurrent Urinary Tract Infections

Alaa  Al Krush; Kawa  Mahmoud; Goran  Abdulla

doi:10.56056/420

Authors

Alaa Al Krush FRCP, Assistant Professor of Medicine and Nephrology, Department of Medicine, College of Medicine, University of Sulaimani, Sulaimaniyah, Iraq.
Kawa Mahmoud CABM (Urology), Lecturer of Urology, Department of Surgery, College of Medicine, University of Sulaimani, Sulaimaniyah, Iraq
Goran Abdulla CABM (Urology), Lecturer of Urology, Department of Surgery, College of Medicine, University of Sulaimani, Sulaimaniyah, Iraq

DOI:

https://doi.org/10.56056/420

Keywords:

Antibiotic Prophylaxis, Nanotechnology Water, Recurrent Urinary Tract Infections

Abstract

Background and objectives: With increasing antimicrobial resistance, high costs, and antibiotic side effects, non-antibiotic options for preventing recurrent urinary tract infections are being explored. This study assessed the effectiveness of nanotechnology-structured water versus regular bottled water and low-dose Trimethoprim.

Methods: A randomized, double-blind, placebo-controlled clinical trial was conducted in Sulaimani city with 300 women who had previously received antibiotic treatment for recurrent urinary tract infections. The participants were divided into three groups: Group M (n=117) received nanotechnology-structured water for 12 months and placebo tablets for six months, administered daily. Group T (n=123) was given 100 mg of Trimethoprim daily for six months and ordinary bottled water for 12 months. Group O (n=109) received only ordinary bottled water for 12 months and placebo tablets for six months. Urine samples were collected at the study's start, during infection episodes, and at the end for urinalysis and cultures.

Results: Antibiotic-treated recurrent urinary tract infections occurred in 29% of participants, varying frequency across groups. Recurrence rates in Groups M and T were similar but significantly lower than in Group O. The time to the first recurrence differed notably among groups, with Group M (nanotechnology-structured water) showing an average of 169.44 days, surpassing Groups T and O. Group M had 9%, Group T 15%, and Group O 63% infections.

Conclusion: Nanotechnology-structured water shows potential as a preventative measure against recurring urinary tract infections, offering an alternative to costly medications with undesirable side effects.

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