Intra-incisional injection of magnesium sulfate for post cesarean pain management
DOI:
https://doi.org/10.56056/amj.2022.174Keywords:
Cesarean section, Pain, Magnesium sulfateAbstract
Background and objectives: cesarean section is estimated for about 30% of child births worldwide and it is one of the most common surgical procedures. Pain relief after cesarean delivery is especially important as the consequences of inadequate pain relief are expressed not only by the mother but by the newborn as well. Magnesium has been reported to produce important analgesic effects including the potentiation of morphine analgesia, attenuation of morphine tolerance and the suppression of neuropathic pain. The objectives of this study were to determine the efficacy of intra-incisional injection of magnesium sulfate for post cesarean pain management as in patient underwent elective cesarean section and the reduced need for extra analgesic use postoperatively.
Methods: a randomized, placebo controlled, single-blinded study with a total of 200 pregnant participants scheduled for cesarean section in Sulaimani maternity teaching hospital, from 1st of May 2016 to 15th of August 2016. Patients were randomly allocated to two groups, those with odd numbers were assigned to case group (100) received 750mg of magnesium sulfate and patients with even numbers assigned to the placebo group (100) received 20mg of normal saline.
Results: The mean Visual Analogue Score after 4 hours, 8 hours, 12 hours and 24hours was significantly less for the intervention (Magnesium sulfate) group when compared with the control (Normal Saline).
Conclusions: Subcutaneous administration of magnesium sulfate in post cesarean section pain management can be used as a successful modality or method for pain management.
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References
- Miller RD, Eriksson LI, Fleisher LA, et al Anesthesia E-Book. Elsevier Health Sciences; 2014. P3310.
- Eshkevari L, Trout K, Damore J. Management of postpartum pain. Journal of midwifery & women's health. 201; 58(6):622-31.
- McDonnell NJ, Keating ML, Muchatuta NA, Pavy TJ, Paech MJ. Analgesia after caesarean delivery. Anaesthesia and intensive care. 2009; 37(4):539-51.
- Kundra S, Singh R, Singh G, Singh T, Jarewal V, Katyal S. Efficacy of magnesium sulphate as an adjunct to ropivacaine in local infiltration for postoperative pain following lower segment caesarean section. Journal of clinical and diagnostic research: JCDR. 2016; 10(4):UC18.
- Hwang JY, Na HS, Jeon YT, Ro YJ, Kim CS, Do SH. IV infusion of magnesium sulphate during spinal anaesthesia improves postoperative analgesia. British journal of anaesthesia. 2009;104(1):89-93.
- Do SH. Magnesium: a versatile drug for anesthesiologists. Korean journal of anesthesiology. 2013; 65(1):4-8.
- Koinig H, Wallner T, Marhofer P, Andel H, Horauf K, Mayer N. Magnesium sulfate reduces intra-and postoperative analgesic requirements. Anesthesia & Analgesia. 1998; 87(1):206-10.
- Behaeen K, Soltanzadeh M, Nesioonpour S, Ebadi A, Olapour A, Aslani SM. Analgesic effect of low dose subcutaneous ketamine administration before and after cesarean section. Iranian Red Crescent Medical Journal. 2014; 16(3):e15506.
- Verstraete S, de Velde Van M. Post-cesarean section analgesia. Acta Anaesthesiologica Belgica. 2012; 63(4):147-67.
- Albrecht E, Kirkham KR, Liu SS, Brull R. Peri operative intravenous administration of magnesium sulphate and postoperative pain: a meta?analysis. Anaesthesia. 2013;68(1):79-90.
- Seyhan TO, Tugrul M, Sungur MO et al. Effects of three different dose regimens of magnesium on propofol requirements, haemodynamic variables and postoperative pain relief in gynaecological surgery. British Journal of Anaesthesia. 2005; 96(2):247-52.
- Taheri A, Haryalchi K, Mansour M, Habibi A. Effect of low-dose (single-dose) magnesium sulfate on postoperative analgesia in hysterectomy patients receiving balanced general anesthesia. Anesthesiol Res Pract. 2015; 2015: 306145
- Bhaskar SB. Case for local infiltration analgesia: Is all the evidence in black and white? Indian journal of anaesthesia. 2015; 59 (1):1-4.
- Ryu JH, Kang MH, Park KS, Do SH. Effects of magnesium sulphate on intraoperative anaesthetic requirements and postoperative analgesia in gynaecology patients receiving total intravenous anaesthesia. British journal of anaesthesia. 2008; 100(3):397-403.
- Apfelbaum JL, Chen C, Mehta SS,. Postoperative pain experience: results from a national survey suggest postoperative pain continues to be undermanaged. Anesthesia & Analgesia. 2003; 97(2):534-40.
- Pazoki S, Eraghi MG, Jamilian M. Incisional Injection of Magnesium Sulfate for Post-Cesarean Section Pain Management. Archives of Critical Care Medicine. 2015; 1(1); e524.
- Mireskandari S, Pestei K, Hajipour A, et al. Effects of preoperative magnesium sulphate on post-cesarean pain, a placebo controlled double blind study. Journal of family & reproductive health. 201; 9(1):29-33.
Rezae M, Naghibi K, Taefnia A. Effect of pre-emptive magnesium sulfate infusion on the post-operative pain relief after elective cesarean section. Advanced biomedical research. 2014:3(164); 1-4
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