Oncological Outcomes of Colorectal Cancer Based on Patients’ Age Group
DOI:
https://doi.org/10.56056/Keywords:
Age group, Colorectal cancer, Hospital-based, Oncological outcomes, Retrospective studyAbstract
Background & objectives: A progressive and significant increase of colorectal cancer has been observed in younger people. Thus, this study evaluated oncological outcomes among patients with colorectal cancer according to their age groups.
Methods: This retrospective cross-sectional hospital-based study was performed from June 2013 to March 2024 at Rizgary Teaching Hospital and Zheen International Hospital on 183 patients with colorectal cancer using their medical records. A data spreadsheet was used to collect patients’ data over eleven years, including gender, surgery, treatment protocol, lymph node status, histopathological findings, distribution of complications, metastasis, recurrences, preoperative and final stages, survival and mortality rates according to their age groups. Then, collected data were analyzed and outcomes were compared between age groups.
Results: Males with CRC constituted 50.3% of patients; of them 54.1% aged <60 years old. Elective surgery was done for 167 (91.2%) patients. Laparoscopic surgeries have been performed for 129 (70.5%) patients. Adjuvant therapy was administered to 27 (14.7%) patients. Lymph node metastasis was seen in 79 (43.2%) patients. Well-differentiated tumor was detected in most of the patients (81.4%). Complications were seen in 41 (22.4%) patients; recurrence was found in 16.9% of patients with colorectal cancer after treatment (p>0.05). The overall 5-year survival rate was 23.8% in the older age (≥ 60 years) group and 34.3% in younger patients (<60 years) (p=0.109). Colorectal cancer killed 30 (16.4%) of patients with no significant difference between the two age groups (p=0.075).
Conclusions: In our study, the oncological outcomes related to both morbidity and mortality from colorectal cancer were not affected by their age.
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